e-Therapeutics (AIM: ETX) is a drug discovery company with a proprietary discovery platform based on advances in network pharmacology and chemical biology.

The Company is applying its platform to the discovery of new drug candidates. The therapeutic focus of the Company’s activity is in immuno-oncology, addressing drug resistance in targeted cancer therapies and anti-infectives. The platform is highly productive, yielding multiple potent and selective molecules at a much higher rate and more quickly than is reported for conventional drug discovery.

e-Therapeutics has a variety of preclinical stage assets, including ETX1153c, a functionally resistance-less antibiotic; ETS2300, telomerase inhibition in anti-cancer; ETS3100, small molecule anti-TNFα; ETS2400, Hedgehog pathway inhibition and ETS5200, broad spectrum antivirals. The Company has recently completed a phase IIb clinical trial for ETS6103, a drug to treat major depressive disorder.

The Company is fully funded to advance its drug discovery programmes. It is based in Oxford and Newcastle, UK.

The Company is listed on the AIM market of the London Stock Exchange (ticker ETX).

Significant shareholdings

  • Invesco – 84,524,060 (31.99%)
  • Woodford Asset Management – 46,807,479 (17.7%)
  • Aviva – 44,073,702 (16.7%)
  • Henderson Group plc– 26,445,958 (10.0%)
  • Malcolm Young – 20,644,958 (7.8%)
  • Octopus Group – 11,097,658 (4.2%)

Read more shareholder information.