Systematic Drug Discovery

In all of life that is relevant to disease, there are millions of proteins. Every drug compound binds in varying degrees to many different proteins. The huge variety of possible protein targets, and the large variety of patterns of possible binding with proteins create an enormous range of possible interactions between a drug molecule and any biological system. For this fundamental reason, the biological effects of a molecule's interactions with pathogenic, pathological and normal cells have been very difficult to predict.

e-Therapeutics has developed proprietary systems biology tools that can predict the biological effect of interference with one or many proteins in a cell. These very fast processes have been shown to predict biological effects accurately.

e-Therapeutics uses these capabilities to search for new drugs across several therapeutic areas; to search for new clinical uses for existing drugs; and to identify the probability of drug-drug interactions and toxicity.

Drug Discovery Programme

e-Therapeutics proprietary discovery program is currently focussed on antimicrobial discovery, and especially on the discovery of compounds with novel modes of action, and so reduced problems of bacterial resistance.